Effect of treatment of hyperuricemia with allopurinol on blood pressure, creatinine clearence, and proteinuria in patients with normal renal functions


Kanbay M. , Ozkara A., Selcoki Y., Isik B., Turgut F., Bavbek N., et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.39, ss.1227-1233, 2007 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 39 Konu: 4
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1007/s11255-007-9253-3
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Sayfa Sayısı: ss.1227-1233

Özet

Background Hyperuricemia has been associated with the development of hypertension, cardiovascular, and renal disease. However, there is no data about the effect of lowering uric acid level on hypertension, renal function, and proteinuria in patients with glomerular filtration rate (GFR) > 60 ml/min. We therefore conducted a prospective study to investigate the benefits of allopurinol treatment in hyperuricemic patients with normal renal function.