Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats


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OTUNCTEMUR A., OZBEK E., CAKIR S. S. , DURSUN M., Cekmen M. B. , Polat E. C. , ...More

INTERNATIONAL BRAZ J UROL, vol.41, no.2, pp.279-287, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1590/s1677-5538.ibju.2015.02.14
  • Title of Journal : INTERNATIONAL BRAZ J UROL
  • Page Numbers: pp.279-287

Abstract

Introduction: Ureteral obstruction is a common pathology and caused kidney fibrosis and dysfunction at late period. In this present, we investigated the antifibrotic and antiinflammatory effects of montelukast which is cysteinyl leukotriene receptor antagonist, on kidney damage after unilateral ureteral obstruction(UUO) in rats.