Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats


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OTUNCTEMUR A., OZBEK E., CAKIR S. S. , DURSUN M., Cekmen M. B. , Polat E. C. , ...More

INTERNATIONAL BRAZ J UROL, vol.41, no.2, pp.279-287, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1590/s1677-5538.ibju.2015.02.14
  • Journal Name: INTERNATIONAL BRAZ J UROL
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.279-287

Abstract

Introduction: Ureteral obstruction is a common pathology and caused kidney fibrosis and dysfunction at late period. In this present, we investigated the antifibrotic and antiinflammatory effects of montelukast which is cysteinyl leukotriene receptor antagonist, on kidney damage after unilateral ureteral obstruction(UUO) in rats.