Anti-inflammatory effect of lycopene on endotoxin-induced uveitis in rats.

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Goncu T., Oguz E. , Sezen H., Kocarslan S., Oguz H. , Akal A., ...More

Arquivos brasileiros de oftalmologia, vol.79, no.6, pp.357-362, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 79 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.5935/0004-2749.20160102
  • Title of Journal : Arquivos brasileiros de oftalmologia
  • Page Numbers: pp.357-362
  • Keywords: Uveitis/chemically induced, Endotoxins, Oxidative stress, Antioxidants, Inflammation, Cytokines, Animals, Disease models, animal, Rats, NF-KAPPA-B, INFLAMMATION IN-VITRO, TOMATO LYCOPENE, HUMAN HEALTH, MACROPHAGES, ASTAXANTHIN, ACTIVATION, MANAGEMENT, DISEASE, MODEL

Abstract

Purpose: We evaluated the efficacy of lycopene, a dietary carotenoid and potent antioxidant, against ocular inflammation and oxidative stress in an experimental uveitis model.