Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia


TAKIR M., KOSTEK O., OZKOK A., ELCIOGLU O. C. , BAKAN A., Erek A., ...Daha Fazla

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.63, ss.924-929, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 63 Konu: 8
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/jim.0000000000000242
  • Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
  • Sayfa Sayıları: ss.924-929

Özet

Background Hyperuricemia is an independent predictor of impaired fasting glucose and type 2 diabetes, but whether it has a causal role in insulin resistance remains controversial. Here we tested the hypothesis that lowering uric acid in hyperuricemic nondiabetic subjects might improve insulin resistance.