The effects of short-term use of granulocyte colony-stimulating factor on bone metabolism in child cancer patients


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Turhan A. B. , Binay C., Bor O., ŞİMŞEK E.

NORTHERN CLINICS OF ISTANBUL, cilt.5, ss.277-281, 2018 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 5 Konu: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.14744/nci.2017.59320
  • Dergi Adı: NORTHERN CLINICS OF ISTANBUL
  • Sayfa Sayıları: ss.277-281

Özet

OBJECTIVE: The granulocyte colony-stimulating factor (G-CSF) is the most commonly used hematopoietic growth factor recombinant DNA technology. It affects bone metabolism by modulating both osteoclast and osteoblast functions. The aim of the present study was to investigate the effects of short-term use of G-CSF on bone metabolism in children with leukemia and solid tumors.