Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells


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Demir U. , KOEHLER A., SCHNEIDER R., SCHWEIGER S., KLOCKER H.

BMC CANCER, vol.14, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14
  • Publication Date: 2014
  • Doi Number: 10.1186/1471-2407-14-52
  • Title of Journal : BMC CANCER

Abstract

Background: Metformin is an approved drug prescribed for diabetes. Its role as an anti-cancer agent has drawn significant attention because of its minimal side effects and low cost. However, its mechanism of anti-tumour action has not yet been fully clarified.