Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension


Collak F. , DEMİR Ü. , Özkanlı S. Ş. , Kurum E., ZERK P. E.

CANCER BIOLOGY & MEDICINE, vol.14, no.4, pp.405-413, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.20892/j.issn.2095-3941.2017.0083
  • Title of Journal : CANCER BIOLOGY & MEDICINE
  • Page Numbers: pp.405-413

Abstract

Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in prostate cancer (PCa) tumorigenesis, we investigated their expression in clinical samples of PCa and cell lines.