Impaired coronary microvascular function and increased intima-media thickness in rheumatoid arthritis

Ciftci, Ozgur; Yilmaz, Sema; Topcu, Semra; Caliskan, MUSTAFA; Gullu, Hakan; Erdogan, Dogan; Pamuk, Baris; Yildirir, Aylin; Muderrisoglu, Haldun

doi:10.1016/j.atherosclerosis.2007.11.013

Impaired coronary microvascular function and increased intima-media thickness in rheumatoid arthritis

Atıf İçin Kopyala

Ciftci O., Yilmaz S., Topcu S., Caliskan M. , Gullu H., Erdogan D., et al.

ATHEROSCLEROSIS, cilt.198, ss.332-337, 2008 (SCI İndekslerine Giren Dergi)

Cilt numarası: 198 Konu: 2
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.atherosclerosis.2007.11.013
Dergi Adı: ATHEROSCLEROSIS
Sayfa Sayısı: ss.332-337

Özet

Background: Rheumatoid arthritis (RA) is associated with excessive cardiovascular mortality. Recently, some studies have shown endothelial dysfunction in RA patients with high inflammatory activity. In addition, it has been suggested that the chronic inflammatory state of RA contributes to accelerated atherosclerosis. Therefore, we aimed to evaluate whether coronary microvascular dysfunction and increased carotid artery intima-media thickness exist in patients with a long history and well controlled disease activity of RA lacking traditional cardiovascular risk factors.