Modulation of the immune response to HBV vaccination by hemodialysis membranes


dede f., Yildiz A., ayli d., colak N., ODABAŞ A. R. , akoglu h., et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.42, ss.1069-1075, 2010 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 42 Konu: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1007/s11255-009-9616-z
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Sayfa Sayısı: ss.1069-1075

Özet

Seroconversion response to Hepatitis B virus (HBV) vaccination is limited in uremic patients because of impaired humoral and cellular immune activity. Recent studies show that high-flux (HF) hemodialysis (HD) membranes can improve T cell functions and decrease the proinflammatory cytokine activation more effectively than low-flux (LF) membranes. In regard to HF membranes may have immune modulator effects; we compared the antibody responses to hepatitis B vaccination between HF HD and LF HD membranes.