Effects of caffeine on placental total nitrite concentration: A 21-day, vehicle-controlled study in rats


ALASEHIRLI B., Cekmen M. B. , NACAK M., BALAT A.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.66, ss.130-137, 2005 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 66 Konu: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.curtheres.2005.04.003
  • Dergi Adı: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
  • Sayfa Sayısı: ss.130-137

Özet

Background: Nitric oxide (NO) is a potent vasodilator that might have an important role in the modulation of maternal and fetal vascular tone during pregnancy. The effects of caffeine intake on maternal and fetal hemodynamic properties during pregnancy have been investigated in several human and animal studies. However, based on a literature search, there has been no study of placental total nitrite (a stable product of NO) concentration (PTNC) in pregnant humans or rats given caffeine.