© 2018 IEEE.Screen readers enable people with visual impairment (VI) to have equal access to written information both on computers and smartphones. This paper presents an overview of screen readers that allow users with VI read the text materials and describe images on the computer screen by using a special software program to synthesize as speech. We study three aspects of the screen readers in terms of their accessibility. First, we invest on developing websites, apps, and software programs by following web content accessibility guidelines to ensure accessibility. We than conduct research on compatibility of the websites, apps, and software programs with screen readers. Last, we inform about descriptions of the images by creating alternative texts.