Multifactor dimensionality reduction analysis of MTHFR, PAI-1, ACE, PON1, and eNOS gene polymorphisms in patients with early onset coronary artery disease

Agirbasli, MEHMET; GÜNEY, AHMET; Ozturhan, H.; Agirbasli, D.; ULUCAN, KORKUT; Sevinc, D.; Kirac, D.; Ryckman, K.; Williams, S.

doi:10.1177/1741826711398806

Multifactor dimensionality reduction analysis of MTHFR, PAI-1, ACE, PON1, and eNOS gene polymorphisms in patients with early onset coronary artery disease

Agirbasli M. A. , GÜNEY A. İ. , Ozturhan H. S. , Agirbasli D., ULUCAN K., Sevinc D., et al.

EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION, cilt.18, ss.803-809, 2011 (SCI İndekslerine Giren Dergi)

Cilt numarası: 18 Konu: 6
Basım Tarihi: 2011
Doi Numarası: 10.1177/1741826711398806
Dergi Adı: EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION
Sayfa Sayısı: ss.803-809

Özet

Background: Association studies in the Turkish population have investigated the single locus effects of different gene polymorphisms on coronary artery disease (CAD). CAD is a complex polygenic disease that involves complex interactions among multiple genetic and environmental conditions.