Is serum Klotho protective against atherosclerosis in patients with type 1 diabetes mellitus?


Keles N., Doğan B., Kalçık M., ÇALIŞKAN M. , Keles N. N. , Aksu F., ...More

JOURNAL OF DIABETES AND ITS COMPLICATIONS, vol.30, no.1, pp.126-132, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1016/j.jdiacomp.2015.09.013
  • Title of Journal : JOURNAL OF DIABETES AND ITS COMPLICATIONS
  • Page Numbers: pp.126-132

Abstract

Objective: Klotho deficiency is associated with several metabolic disorders. Two dimensional (2D) longitudinal strain (IS) of left ventricle (LV), carotid artery intima-media thickness (CIMT), flow-mediated dilation (FMD) of brachial artery and epicardial fat thickness (EFT) have been reported to be early predictors of atherosclerosis. We aimed to investigate the relationship between serum Klotho levels and these early predictors of atherosclerosis in patients with type 1 diabetes mellitus (DM).