Higher dose intra-arterial milrinone and intra-arterial combined milrinone-nimodipine infusion as a rescue therapy for refractory cerebral vasospasm


Duman E., Karakoc F., Pinar H. U. , Dogan R., Firat A., Yildirim E.

INTERVENTIONAL NEURORADIOLOGY, vol.23, no.6, 2017 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.1177/1591019917732288
  • Journal Name: INTERVENTIONAL NEURORADIOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Keywords: Endovascular therapy, refractory cerebral vasospasm, intra-arterial milrinone infusion, subarachnoid hemorrhage, ANEURYSMAL SUBARACHNOID HEMORRHAGE, METAANALYSIS, MANAGEMENT, VERAPAMIL

Abstract

Background: Cerebral vasospasm (CV) is a major cause of delayed morbidity and mortality in patients with subarachnoid hemorrhage (SAH). Various cerebral protectants have been tested in patients with aneurysmal SAH. We aimed to research the success rate of treatment of CV via intra-arterial milrinone injection and aggressive pharmacological therapy for refractory CV.