Protective effect of a nuclear factor kappa B inhibitor, pyrolidium dithiocarbamate, in the kidney of rats with nephrolithiasis induced by ethylene glycol


TUGCU V., OZBEK E., KEMAHLI E., Cekmen M. B. , CANER N., SOMAY A., et al.

JOURNAL OF ENDOUROLOGY, cilt.21, ss.1097-1106, 2007 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 21 Konu: 9
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1089/end.2007.0074
  • Dergi Adı: JOURNAL OF ENDOUROLOGY
  • Sayfa Sayısı: ss.1097-1106

Özet

Purpose: To study the protective effects of a selective nuclear factor kappa B (NF-kappa B) inhibitor, pyrolidium dithiocarbamate (PDTC), on ethylene glycol-induced crystal deposition in the renal tubules, renal toxicity, as well as inducible nitric oxide synthase (iNOS) and NF-kappa B activities in rat kidneys.