Diffusion-weighted imaging evaluation of subtle cerebral micro structural changes in intrauterine fetal hydrocephalus

Erdem G., Celik O., Hascalik S., Karakas H. M. , Alkan A., Firat A. K.

MAGNETIC RESONANCE IMAGING, vol.25, no.10, pp.1417-1422, 2007 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 10
  • Publication Date: 2007
  • Doi Number: 10.1016/j.mri.2007.03.028
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1417-1422
  • Keywords: fetal, hydrocephaly, diffusion reduction, diffusion-weighted MRI, RAT-BRAIN, ENERGY-METABOLISM, COEFFICIENT ADC, WHITE-MATTER, BLOOD-FLOW, LACTATE, MRI, CHILDREN, SEIZURES, PYRUVATE


Objective: Hydrocephalus is an important etiological factor in neurological decline. With the advent of fetal ultrasound, fetal hydrocephalus is now more frequently detected than in the past. Ultrasonography (USG) provides information on general morphology, but microstructural changes that may play a prognostic role are beyond the resolution of that technique. These changes may theoretically be revealed by diffusion-weighted magnetic resonance imaging (DW-MRI). In this study, our preliminary findings of DW-MRI on the hydrocephalic fetuses are presented.