COMPARISON OF ANTINOCICEPTIVE EFFECTS OF ANALGESICS IN A CHEMICAL MODEL OF VISCERAL PAIN IN MICE


EKINCI O., Pelit T., Gül F., Subaşı D., Aydın N., TERZİOĞLU BEBİTOĞLU B. , et al.

NOBEL MEDICUS, cilt.7, ss.40-44, 2011

  • Cilt numarası: 7 Konu: 2
  • Basım Tarihi: 2011
  • Dergi Adı: NOBEL MEDICUS
  • Sayfa Sayısı: ss.40-44

Özet

Objective: There are several experimental methods to propose the efficacy of pharmacological agents to test nociception and analgesia. Acetic acid induced writhing test is an established method for studying visceral pain. The aim of this study is to compare efficacy and potency orders of tramadol, lornoxicam and paracetamol in a mice model and supply evidence for clinicians dealing with pre-emptive analgesia.