A CD30(-) Transformed Mycosis Fungoides Case Responding Very Well to Systemic Bexarotene and Methotrexate


Zindanci I., Kavala M., Turkoglu Z., Can B., ÖZTÜRK E. , Zemheri E., et al.

INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS, cilt.13, ss.127-129, 2014 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 13 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1177/1534734614534978
  • Dergi Adı: INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
  • Sayfa Sayısı: ss.127-129

Özet

The course of mycosis fungoides (MF) is indolent except when transformation to a large T-cell lymphoma occurs. The diagnosis of transformed MF relies on the presence of more than 25% of large cells on biopsy of an MF lesion. Treatment of transformed MF is a major challenge as these patients have poor outcome. Here, we report a 61-year-old man presenting with tumoral ulcer on the plantar area of the foot who was diagnosed cutaneous CD30(-) large cell transformed MF and treated with systemic methotraxate and bexarotene therapy.