Is low-level laser therapy or ozone therapy more effective on autogenous block onlay bone grafting?

Acar A. H.

3rd International Eurasian Conference on Biological and Chemical Sciences, Ankara, Turkey, 20 - 21 March 2020, pp.321

  • Publication Type: Conference Paper / Summary Text
  • City: Ankara
  • Country: Turkey
  • Page Numbers: pp.321


This study aims to analyze the effect of the low-level laser therapy (LLLT) and ozone therapy (OT) on the bone healing of

autogenous block onlay bone grafting (BOG) in rat calvaria. Material and Methods: A total of 30 Wistar male rats were

used. A 5-mm-diameter trephine bur was used to collect BOG on the left side of the parietal bone. BOG was fixed with

Histoacryl ® glue (cyanoacrylate, N-asetil 2 butyl sistein, B. Braun Melsungen AG, Germany) on the right side of the

parietal bone of each rat calvarium. The animals were randomly divided into 3 groups as follows: the control group (n = 10),

which received no therapy; the LLLT group (n = 10), which received only LLLT (120 seconds, 3 times a week for 2 weeks)

and OT group (n = 10) (30 seconds, 3 times a week for 2 weeks). After 1 month, all the rats were killed, and the sections

were examined to evaluate the presence of inflammatory infiltrate, connective tissue, and new bone formation areas. Results

Histomorphometry revealed no significant difference between all groups. OT group had higher percentage of new bone

formation (P < 0.05). Conclusion: Future randomized clinical trials with larger sample sizes and longer follow-ups are

needed to further validate this treatment protocols.