Assessment of the thyroid nodules by Tc-99m Tetrofosmin scintigraphy.


Akçay G., USLU SINAV H., Varoğlu E., Tekin S., Gündoğdu C.

Assessment of the thyroid nodules by Tc-99m Tetrofosmin scintigraphy. Britsh Journal of Clinical Practice., no.51, pp.5-7, 1997 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Publication Date: 1997
  • Journal Name: Assessment of the thyroid nodules by Tc-99m Tetrofosmin scintigraphy. Britsh Journal of Clinical Practice.
  • Journal Indexes: Science Citation Index Expanded
  • Page Numbers: pp.5-7

Abstract

Thyroid nodularity is a common finding. The incidence of thyroid cancer in the general population is estimated at 0.1%. Thyroid nodules are evaluated by palpation, ultrasonography, radionuclide scintigraphy and fine-needle aspiration cytology. Routine thyroid scintigraphy is made by using Tc-99m-pertechnetate or the I-131 and I-123 scintigraphic method. Tc-99m-tetrofosmin accumulates in the myocardium, skeletal muscle, liver, spleen breast tissue, kidney and normal and pathological thyroid tissue. We investigated 36 patients (28 females and 8 males) with solitary and/or multiple thyroid nodules. All the patients were euthyroid, and their thyroid nodules were diagnosed by palpation and ultrasound examination. Thyroid scintigraphy was applied by Tc-99m-pertechnetate, then thyroid fine-needle aspiration biopsy was performed. Finally, Tc-99m-tetrofosmin scintigraphy was carried out. Five patients (14.8%) had differential thyroid carcinoma, 23 (63.8%) had thyroid adenoma, 1 (0.02%) had Riedel's thyroiditis and 7 (19.4%) had follicular cyst. We detected 80% uptake in the early phase and 100% in the late phase by Tc-99m-tetrofosmin scintigraphy in the differentiated thyroid carcinoma group. In summary, we claim that Tc-99m-tetrofosmin may be an important scintigraphic method to identify thyroid malignancy from benign thyroid pathologies.