TLR4 Asp299Gly and Thr399Ile and TLR2 intron 2 microsatellite gene polymorphism in patients with acute biliary pancreatitis: Does it cause the disease?


Creative Commons License

Anilir E., Ozen F., Ozemir I. A. , YILDIRIM İ. H. , Bilgic C., ALİMOĞLU O.

TURKISH JOURNAL OF SURGERY, vol.34, no.3, pp.191-197, 2018 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.5152/turkjsurg.2017.3828
  • Title of Journal : TURKISH JOURNAL OF SURGERY
  • Page Numbers: pp.191-197

Abstract

Objectives: There has been coverage of Toll-like receptor 4 and Toll-like receptor 2 gene polymorphisms in inflammatory episodes in a number of studies. In view of the inflammatory nature of acute pancreatitis, we aimed to determine the predictive value of mutations in Asp299Gly and Thr399Ile of the Toll-like receptor 4 gene, and the intron 2 microsatellite polymorphism of the Toll-like receptor 2 gene on the occurrence of acute biliary pancreatitis.