Therapeutic apheresis for severe hypertriglyceridemia in pregnancy


Basar R., Uzum A. K. , Canbaz B. , Dogansen S. C. , Kalayoglu-Besisik S., Altay-Dadin S., et al.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.287, ss.839-843, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 287 Konu: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00404-013-2786-z
  • Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Sayfa Sayısı: ss.839-843

Özet

During pregnancy, a progressive increase in serum triglyceride (TG) and cholesterol levels is observed whereas TG levels mostly remain < 300 mg/dl. In women with genetic forms of hypertriglyceridemia, pregnancy may cause extremely elevated TG levels leading to potentially life-threatening pancreatitis attacks and chylomicronemia syndrome. The only safe medical treatment option during pregnancy is omega-3 fatty acids, which have moderate TG lowering effects. Therapeutic apheresis could be used as primary treatment approach during pregnancy.