TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.27, no.2, pp.214-217, 2018 (Journal Indexed in ESCI)
Article / Article
Title of Journal :
TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
Protein-C (PC) is a vitamin-K-dependent anticoagulant proenzyme produced by the liver. PC deficiency may cause both venous and arterial thromboses. In patients with PC deficiency, warfarin further decreases PC activity and causes thrombosis of skin arterioles leading to skin necrosis.