Diagnostic Value of Strain Echocardiography, Galectin-3, and Tenascin-C Levels for the Identification of Patients with Pulmonary and Cardiac Sarcoidosis

Kul Ş., Ozcelik H. K. , Uyarel H., KARAKUS G., Guvenc T. S. , Yalcinsoy M., ...More

LUNG, vol.192, no.4, pp.533-542, 2014 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 192 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.1007/s00408-014-9586-5
  • Journal Name: LUNG
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.533-542


Cardiac involvement in sarcoidosis has been associated with poor prognosis. We evaluated myocardial contractility quantitatively in a cohort of pulmonary sarcoidosis (PS) patients with and without cardiac involvement. We also studied markers of fibrosis (tenascin-C [Tn-C] and galectin-3 [Gl-3]) as diagnostic tools for PS and cardiac sarcoidosis (CS).