Biochemical effects of experimental epidural hematoma on brain parenchyma of rats

Balikci M., Koc K., ANIK İ., ANIK Y., Cekmen M. B. , YAZIR Y., ...More

NEUROLOGICAL RESEARCH, vol.30, no.5, pp.450-456, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1179/016164107x251637
  • Title of Journal : NEUROLOGICAL RESEARCH
  • Page Numbers: pp.450-456


Introduction: The management of epidural hematoma is classified into surgical or conservative treatment according to clinical and radiologic parameters. In the recent years, the number of paper suggesting conservative management has been increasing. The experimental works that have been performed are based on especially the effects of epidural hematomas. Basic pathophysiologic factors on ischemia result of brain trauma are based on biochemical mediators. Nitric oxide (NO) and malondialdehyde (MDA) are the substances that play important roles in brain damage after trauma.