Influence of conversion from calcineurin inhibitors to everolimus on fibrosis, inflammation, tubular damage and vascular function in renal transplant patients


Alpay N., Ozkok A., Caliskan Y., Akagun T., Cinar S. A. , Deniz G., et al.

CLINICAL AND EXPERIMENTAL NEPHROLOGY, cilt.18, ss.961-967, 2014 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 18 Konu: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s10157-014-0939-4
  • Dergi Adı: CLINICAL AND EXPERIMENTAL NEPHROLOGY
  • Sayfa Sayısı: ss.961-967

Özet

Conversion from calcineurin inhibitor (CNI) to mTOR inhibitors may reduce and even halt the progression of chronic allograft dysfunction (CAD) which is the most important cause of renal allograft loss. We aimed to investigate the effects of conversion from CNI to everolimus on parameters of fibrosis, inflammation, glomerulotubular damage and vascular functions in renal transplant recipients.