Investigation of Bosentan's Effects on Pulmonary Contusion Created by Blunt Thoracic Trauma in Rats


Gercel G., Aksu B., Ozkanli S. Ş. , Uzun H., Aksu F., Ozatman E., ...More

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, vol.30, pp.71-78, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30
  • Publication Date: 2020
  • Doi Number: 10.1055/s-0039-1697908
  • Title of Journal : EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Page Numbers: pp.71-78

Abstract

Introduction Bosentan is an endothelin-1 receptor antagonist with anti-inflammatory, antioxidant, and antiproliferative effects. We aimed to evaluate its effects on lung tissue in a pulmonary contusion (PC) model.