Investigation of Bosentan's Effects on Pulmonary Contusion Created by Blunt Thoracic Trauma in Rats


Gercel G., Aksu B., Ozkanli S. Ş. , Uzun H., Aksu F., Ozatman E., et al.

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, cilt.30, ss.71-78, 2020 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 30
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1055/s-0039-1697908
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Sayfa Sayısı: ss.71-78

Özet

Introduction Bosentan is an endothelin-1 receptor antagonist with anti-inflammatory, antioxidant, and antiproliferative effects. We aimed to evaluate its effects on lung tissue in a pulmonary contusion (PC) model.