Plasma pentraxin 3 levels in preeclamptic patients

Turkmen O., Mollaoglu S., Goynumer G., Isbilen B.

CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, vol.42, no.2, pp.220-223, 2015 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.12891/ceog1825.2015
  • Page Numbers: pp.220-223


The authors evaluated plasma pentraxin 3 (PTX 3) levels in preeclamptic patients and determined the relationship between albuminuria and plasma PTX 3 levels. During a period of one year, 29 patients with severe or mild preeclampsia and 49 healthy pregnant women were included in the cross-sectional study. The two groups were compared each other with PTX 3 levels. The relationship between PTX 3 levels and urea, creatinine, AST, ALT, CRP, LDH, platelet count, and spot urine protein/creatinine rate were evaluated. PTX 3 level was significantly high in the preeclamptic group (p < 0.05). No significant correlation was found between serum PTX 3 level and urea, creatinine, AST, ALT, CRP, LDH, platelet, and spot urine protein/creatinine rate (p > 0.05). PTX 3 is a biochemical parameter that shows endothelial dysfunction. The authors believe that PTX 3 can be a valuable parameter to predict preeclampsia according to the significantly high PTX 3 levels in preeclamptic patients.