Determining the cut-off values of tumor diameter, degree of extraprostatic extension, and extent of surgical margin positivity with regard to biochemical recurrence of prostate cancer after radical prostatectomy


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Kir G., Arikan E., Seneldir H. , Ankarali H. , Oznergiz S., Olgun Z., ...Daha Fazla

ANNALS OF DIAGNOSTIC PATHOLOGY, cilt.44, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: The pre-biopsy (bx) prostate-specific antigen (PSA) level, tumor volume/diameter, degree of extraprostatic extension (EPE), and extent of surgical margin positivity have been shown to be significant prognostic parameters of biochemical recurrence (BCR) after radical prostatectomy. The present study assessed the cut-off values of the pre-bx PSA level, maximum tumor diameter, radial and circumferential distances of EPE, and circumferential length of surgical margin (SM) positivity with regard to BCR.