Role of serum and urine transforming growth factor beta 1, matrix metallopeptidase 9, tissue inhibitor of metalloproteinase 2, and nerve growth factor beta levels and serum neutrophil-to-lymphocyte ratio in predicting recurrence and progression risks in patients with primary non-muscle invasive bladder cancer.


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Efiloğlu Ö., Başok B., Turan T., Toprak T., Erol B., Çaşkurlu T., ...More

Turkish journal of urology, vol.46, pp.206-212, 2020 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46
  • Publication Date: 2020
  • Doi Number: 10.5152/tud.2020.19186
  • Title of Journal : Turkish journal of urology
  • Page Numbers: pp.206-212
  • Keywords: Bladder cancer, MMP-9, NGF-beta, neutrophil-to-lymphocyte ratio, TGF-beta 1, TIMP-2, TRANSITIONAL-CELL CARCINOMA, EXPRESSION, RECEPTORS

Abstract

Objective: The current study aimed to examine the correlation between serum and urine transforming growth factor beta 1 (TGF-beta 1), matrix metallopeptidase 9 ( MMP-9), tissue inhibitor of metalloproteinase 2 (TIMP-2), and nerve growth factor beta (NGF-beta) levels and serum neutrophil-to-lymphocyte ratio (NLR) as well as the recurrence and progression risks of non-muscle invasive bladder cancer (NMIBC).