Low indoleamine 2,3-dioxygenase activity in persistent food allergy in children


Buyuktiryaki B., ŞAHİNER Ü. M. , GİRGİN G., BİRBEN E., UYSAL SOYER Ö., Cavkaytar Ö. , ...More

ALLERGY, vol.71, no.2, pp.258-266, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 71 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1111/all.12785
  • Title of Journal : ALLERGY
  • Page Numbers: pp.258-266
  • Keywords: cell culture, children, food allergy, indoleamine 2, 3-dioxygenase (IDO), tolerance, SUPPRESS TRYPTOPHAN BREAKDOWN, DENDRITIC CELLS, INTERFERON-GAMMA, SERUM TRYPTOPHAN, TOXOPLASMA-GONDII, HUMAN-FIBROBLASTS, INDUCTION, EXPRESSION, TOLERANCE, ACID

Abstract

BackgroundIndoleamine 2,3-dioxygenase (IDO), which degrades tryptophan (Trp) to kynurenine (Kyn), has been demonstrated to contribute to modulation of allergic responses. However, the role of IDO in food allergy has not yet been elucidated.