Selective nuclear factor kappa-B inhibitors, pyrolidium dithiocarbamate and sulfasalazine, prevent the nephrotoxicity induced by gentamicin


TUGCU V., OZBEK E., TASCI A. I. , KEMAHLI E., SOMAY A., BAS M., et al.

BJU INTERNATIONAL, cilt.98, ss.680-686, 2006 (SCI İndekslerine Giren Dergi)

Özet

OBJECTIVE To investigate the effect of selective nuclear factor kappa-B (NF kappa-B) inhibitors, pyrolidium dithiocarbamate (PD) and sulfasalazine (SZ) on renal tubular necrosis and inducible nitric oxide synthase (iNOS) and NF kappa-B expression induced by gentamicin in rats.