Low serum insulin-like growth factor-1 in patients with erectile dysfunction


Otunctemur A., Ozbek E., Sahin S., Ozcan L., Dursun M., Polat E. C. , et al.

BASIC AND CLINICAL ANDROLOGY, cilt.26, 2016 (ESCI İndekslerine Giren Dergi)

Özet

Objective: Endothelial dysfunction and microvascular damage play a crurical role in the pathogenesis of erectile dysfunction (ED). Insulin-like growth factor-1 (IGF-1) is one of the growth factors that have a wide range of biologic effects. IGF-1 is an important mediator of cell growth, differentiation and transformation in various tissues. The purpose of the current study was to determine the association between IGF-1 levels and ED.