The effect of transforming growth factor beta 1 (TGF-beta 1) on the regenerate bone in distraction osteogenesis - A biomechanical, histologic and immunohistochemical study on rabbits


ÖZKAN K.

GROWTH FACTORS, cilt.25, ss.101-107, 2007

  • Cilt numarası: 25 Konu: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1080/08977190701352594
  • Dergi Adı: GROWTH FACTORS
  • Sayfa Sayısı: ss.101-107

Özet

Distraction osteogenesis is a well established clinical treatment for limb length dicrepancy and skeletal deformities. Transforming growth factor beta 1 (TGF-beta 1) is a multifunctional peptide which controls proliferation and expression of cells specific to bone like chondrocytes, osteoblasts, osteoclasts including mesenchymal precursor cells.