ANNALS OF OPHTHALMOLOGY, vol.37, no.4, pp.281-284, 2005 (Journal Indexed in SCI)
The acute effects of 50 mg of sildenafil on tear functions were evaluated in 12 impotent patients. Mean tear break-up time, cotton thread, and Schirmer I tests were 19.42 +/- 6.45 s, 13.92 +/- 6.63 mm, and 16.58 +/- 12.19 mm, respectively before sildenafil and 20.33 +/- 10.40 s, 10.92 +/- 6.14 mm, and 18.08 +/- 12.36 mm, respectively, 1 hour after sildenafil. The results suggest that sildenafil does not adversely affect tear functions.