Protective effect of beta-glucan on acute lung injury induced by lipopolysaccharide in rats

Iraz M., IRAZ M., Esrefoglu M., Aydin M. S.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.45, no.2, pp.261-267, 2015 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.3906/sag-1312-1
  • Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.261-267

Abstract

Background/aim: Lipopolysaccharide (LPS)-induced endotoxemia can cause serious organ damage such as acute lung injury and death by triggering the secretion of proinflammatory cytokines and acute-phase reactants. The goal of this study was to evaluate the effects of alpha-glucan on inflammatory mediator levels and histopathological changes in LPS-induced endotoxemia.