Protective effect of beta-glucan on acute lung injury induced by lipopolysaccharide in rats

Iraz M., IRAZ M., Esrefoglu M., Aydin M. S.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, ss.261-267, 2015 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 45 Konu: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1312-1
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayısı: ss.261-267

Özet

Background/aim: Lipopolysaccharide (LPS)-induced endotoxemia can cause serious organ damage such as acute lung injury and death by triggering the secretion of proinflammatory cytokines and acute-phase reactants. The goal of this study was to evaluate the effects of alpha-glucan on inflammatory mediator levels and histopathological changes in LPS-induced endotoxemia.