A systematic review was conducted to use recent and relevant literature resources in examining the sexual counseling with the PLISSIT model. Electronic literature search was conducted on Medline, Science Direct, Google Scholar, and PubMed between January 1, 2011, and March 1, 2021. 14 studies were included in the systematic review. The mostly used study design was randomized controlled trial. It was determined that PLISSIT model on sexual counseling is an effective, simple, useful, and cost-effective counseling method.