Ghrelin Alleviates Spinal Cord Injury in Rats Via Its Anti-inflammatory Effects


ERŞAHİN M.

TURKISH NEUROSURGERY, cilt.21, ss.599-605, 2011 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 21 Konu: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5137/1019-5149.jtn.4736-11.0
  • Dergi Adı: TURKISH NEUROSURGERY
  • Sayfa Sayısı: ss.599-605

Özet

AIM: Spinal cord injury (SCI) leads to an inflammatory response that generates substantial secondary damage within the tissue besides the primary damage. Ghrelin, 28 amino-acid peptide, has been shown to modulate the release of proinflammatory cytokines and exert anti-inflammatory effects. The aim of the current study was to investigate the anti-inflammatory effects of ghrelin, in a rat model of SCI.