Synthesis of Dy-Y co-substituted manganese-zinc spinel nanoferrites induced anti-bacterial and anti-cancer activities: Comparison between sonochemical and sol-gel auto-combustion methods


Almessiere M. A. , Slimani Y., Rehman S., Khan F. A. , Polat E., Sadaqat A., ...More

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, vol.116, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116
  • Publication Date: 2020
  • Doi Number: 10.1016/j.msec.2020.111186
  • Journal Name: MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, Aerospace Database, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, Communication Abstracts, Compendex, EMBASE, INSPEC, MEDLINE, Metadex, Civil Engineering Abstracts
  • Keywords: Spinel ferrites, Sonochemical synthesis, Sol-gel route, Magnetic properties, Anticancer-antibacterial activity, MN-ZN FERRITES, DC-DC CONVERTER, MAGNETIC-PROPERTIES, MAGNETOOPTICAL PROPERTIES, ELECTRICAL-PROPERTIES, ION SUBSTITUTION, NANOPARTICLES, FABRICATION, ABSORPTION, OXIDE

Abstract

This study described the beneficial properties of ultrasonic irradiation approach to synthesize the spinel-type DyY co-substituted Mn-Zn nanospinel ferrites (NSFs). We have used two different approaches like citrate sol-gel combustion and ultrasonic irradiation routes to produced series of Mn0.5Zn0.5Fe2-2x(DyxYx)O-4 (0.0 <= x <= 0.05) NSFs (DyY-MnZn NSFs). The structure and morphology of NSFs X-was examined by using XRD, EDX, SEM and TEM methods. We have found that spinel ferrites and hematite phase in DyY-MnZn NSFs produced by citrate sol-gel, while DyY-MnZn NSFs created by ultrasonic irradiation contain a pure phase of spinel ferrite. TEM analysis revealed the spherical nanoparticles with fairly uniform size. We have also analyzed the biological applications of DyY-MnZn NSFs prepared by both methods (ultrasonication and sol-gel) by examining their anti-cancer and anti-bacterial (Escherichia coli and Staphylococcus aureu) activities. We have found that both methods produced inhibitory actions on colon cancer cells (HCT-116) and bacterial cells, whereas, no inhibitory action was observed when examined on normal and non-cancerous cells (HEK-293).