Synthesis of Dy-Y co-substituted manganese-zinc spinel nanoferrites induced anti-bacterial and anti-cancer activities: Comparison between sonochemical and sol-gel auto-combustion methods

Almessiere M. A. , Slimani Y., Rehman S., Khan F. A. , Polat E. , Sadaqat A., ...Daha Fazla

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, cilt.116, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 116
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.msec.2020.111186


This study described the beneficial properties of ultrasonic irradiation approach to synthesize the spinel-type DyY co-substituted Mn-Zn nanospinel ferrites (NSFs). We have used two different approaches like citrate sol-gel combustion and ultrasonic irradiation routes to produced series of Mn0.5Zn0.5Fe2-2x(DyxYx)O-4 (0.0 <= x <= 0.05) NSFs (DyY-MnZn NSFs). The structure and morphology of NSFs X-was examined by using XRD, EDX, SEM and TEM methods. We have found that spinel ferrites and hematite phase in DyY-MnZn NSFs produced by citrate sol-gel, while DyY-MnZn NSFs created by ultrasonic irradiation contain a pure phase of spinel ferrite. TEM analysis revealed the spherical nanoparticles with fairly uniform size. We have also analyzed the biological applications of DyY-MnZn NSFs prepared by both methods (ultrasonication and sol-gel) by examining their anti-cancer and anti-bacterial (Escherichia coli and Staphylococcus aureu) activities. We have found that both methods produced inhibitory actions on colon cancer cells (HCT-116) and bacterial cells, whereas, no inhibitory action was observed when examined on normal and non-cancerous cells (HEK-293).