A Prospective Study of Nonsuppurative Complications of Streptococcal Pharyngitis

Arslan F.

Journal of Microbiology and Infectious Diseases, cilt.6, ss.8-11, 2016 (Diğer Kurumların Hakemli Dergileri)

  • Cilt numarası: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5799/ahinjs
  • Dergi Adı: Journal of Microbiology and Infectious Diseases
  • Sayfa Sayıları: ss.8-11


Objective: Group A Streptococci (GAS) is the most important bacterial cause of pharyngitis because antibiotic therapy can be prescribed and failure to treat it is associated with suppurative and nonsuppurative complications. Nonsup­purative complications occur after a latency period of a few weeks and include acute rheumatic fever, scarlet fever, streptococcal toxic shock syndrome, acute glomerulonephritis, and pediatric autoimmune neuropsychiatric disorder associated with group A streptococci. The aim of this study is to investigate the frequency of nonsuppurative complica­tions in properly treated children with GAS pharyngitis.

Methods: We investigated the frequency of nonsuppurative complications in 1030 proven GAS pharyngitis patients between 5 and 15 years old who were properly treated by a prospective observational study. All patients diagnosed with GAS pharyngitis were followed prospectively using a standard form for six months by monthly phone calls.

Results: All the isolates recovered from the patients were susceptible to penicillin. Twentyseven (2.6%) patients devel­oped scarlet fever and none of the other nonsuppurative complications developed in our patient cohort.