Deterioration of bone quality by long-term magnetic field with extremely low frequency in rats

Gurgul S., Erdal N., Yilmaz S. N. , Yildiz A., Ankarali H.

BONE, vol.42, no.1, pp.74-80, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1016/j.bone.2007.08.040
  • Title of Journal : BONE
  • Page Numbers: pp.74-80


The aim of our study was to investigate the effects of long-term (45 days) magnetic field (50 Hz, 1 mT; MF) on femur biomechanical parameters of rats. Bone mineral density (BMD) and histological investigation were also evaluated. For this purpose, twenty-four 8-week-old, Wistar-Albino female and male rats were assigned randomly to female control (FC) and MF-exposed rats (F-MF); male control (MC) and MF-exposed rats (M-MF). BMD was measured by dual-energy X-ray absorptiometry. Cross-sectional area of the femoral shaft was evaluated by computerized tomography. Biomechanical measurements were performed at the mid-diaphysis of the left femur with tensile test. Maximum load, displacement, stiffness, energy absorption capacity (structural properties); ultimate stress, ultimate strain, elastic modulus and toughness (material properties) were calculated. Diaphysial cortical bone thickness was measured by using histological method from the right femur.