NEW ENGLAND JOURNAL OF MEDICINE, vol.383, no.11, pp.1040-1049, 2020 (Peer-Reviewed Journal)
Article / Article
NEW ENGLAND JOURNAL OF MEDICINE
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BackgroundDarolutamide is a structurally distinct androgen-receptor inhibitor that is approved for the treatment of nonmetastatic, castration-resistant prostate cancer. In the planned primary analysis of a phase 3 trial, the median metastasis-free survival was significantly longer with darolutamide (40.4 months) than with placebo (18.4 months). The data for the analysis of overall survival were immature at the time of the primary analysis.