High ceruloplasmin levels are associated with obsessive compulsive disorder: a case control study

Vırıt O., SELEK S., Bulut M., Savaş H. A. , Çelik H., Erel Ö., ...Daha Fazla

BEHAVIORAL AND BRAIN FUNCTIONS, cilt.4, 2008 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1186/1744-9081-4-52


Background: Alterations in ceruloplasmin are currently assumed as one of the mechanisms underlying the development of a number of neurodegenerative disorders. Several studies indicate that elevated serum ceruloplasmin levels may play a role in schizophrenia by exacerbating or perpetuating dopaminergic dysregulation. No study investigating the relationship between ceruloplasmin and obsessive-compulsive disorder (OCD) has been published to date. Nowadays OCD is increasingly speculated to be a different disorder than other anxiety disorders, and rather is considered to be more similar to psychotic disorders. The objective of this study to explore whether there is an association of ceruloplasmin with OCD as in schizophrenia.