Neonatal Seizure as a Manifestation of Unrecognized Maternal Hyperparathyroidism


KORKMAZ H. A. , Ozkan B. , TEREK D., DIZDARER C., Arslanoglu S.

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.5, no.3, pp.206-208, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.4274/jcrpe.1037
  • Title of Journal : JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Page Numbers: pp.206-208
  • Keywords: Hypocalcemia, transient hypoparathyroidism, maternal hyperparathyroidism, maternal hypercalcemia, PREGNANCY, MANAGEMENT

Abstract

Maternal hypercalcemia suppresses parathyroid activity in the fetus resulting in impaired parathyroid responsiveness to hypocalcemia after birth. Resultant hypocalcemia may be severe and prolonged and rarely may lead to convulsions. Here, we present a newborn infant admitted to the pediatric emergency department at age two weeks with recurrent tonic convulsions due to asymptomatic maternal hyperparathyroidism and vitamin D deficiency. Physicians should be aware that undiagnosed maternal hyperparathyroidism can cause severe hypocalcemia in the newborn.