The role of chemokine and chemokine receptor gene variants on the susceptibility and clinicopathological characteristics of bladder cancer


Kucukgergin C., Isman F. K. , Dasdemir S., Cakmakoglu B., Sanli O., Gokkusu C., et al.

GENE, cilt.511, ss.7-11, 2012 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 511 Konu: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.gene.2012.09.011
  • Dergi Adı: GENE
  • Sayfa Sayısı: ss.7-11

Özet

The gene variants of the chemokine and chemokine receptor genes associated with inflammation may be involved in cancer initiation and progression. The aim of this study was to explore the possible association of monocyte chemoattractant protein-1 (MCP-1) A2518G, stromal cell derived factor 1 (SDF-1) 3'A and chemokine receptors CCR2A V64I, CCR5 Delta 32, CCR5 59029 and CXCR4 gene polymorphisms with the risk and clinicopathological characteristics of bladder cancer (BC) in a Turkish population.