Urotensin-II level and its association with oxidative stress in early diabetic nephropathy

Tabur S., Korkmaz H., Eren M. A. , Oguz E. , Sabuncu T., Aksoy N.

JOURNAL OF DIABETES AND ITS COMPLICATIONS, vol.29, no.1, pp.115-119, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jdiacomp.2014.07.011
  • Title of Journal : JOURNAL OF DIABETES AND ITS COMPLICATIONS
  • Page Numbers: pp.115-119
  • Keywords: Diabetic nephropathy, Urotensin-II, Oxidative stress, Paraoxonase, Arylesterase, AUTOMATED-METHOD, DISEASE, RECEPTOR

Abstract

Objective: Diabetic nephropathy is the most common cause of end stage renal failure. Early treatment of diabetic nephropathy depends on understanding the underlying mechanisms of the disease. In this study we investigated the role of U-II in early nephropathy and its association with oxidative stress, paraoxonase (PON)-1 and arylesterase.