Urotensin-II level and its association with oxidative stress in early diabetic nephropathy

Tabur S., Korkmaz H., Eren M. A. , Oguz E., Sabuncu T., Aksoy N.

JOURNAL OF DIABETES AND ITS COMPLICATIONS, vol.29, no.1, pp.115-119, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jdiacomp.2014.07.011
  • Journal Name: JOURNAL OF DIABETES AND ITS COMPLICATIONS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.115-119
  • Keywords: Diabetic nephropathy, Urotensin-II, Oxidative stress, Paraoxonase, Arylesterase, AUTOMATED-METHOD, DISEASE, RECEPTOR

Abstract

Objective: Diabetic nephropathy is the most common cause of end stage renal failure. Early treatment of diabetic nephropathy depends on understanding the underlying mechanisms of the disease. In this study we investigated the role of U-II in early nephropathy and its association with oxidative stress, paraoxonase (PON)-1 and arylesterase.