Cirugia espanola, cilt.96, ss.620-626, 2018 (SCI Expanded İndekslerine Giren Dergi)
Background: Nodular thyroid disease possesses the potential to harbor malignancy. Our aim
was to evaluate the significance of cervical diffusion-weighted magnetic resonance imaging
(DW-MRI) for the detection of malignant thyroid nodules.
Methods: Sixty-five thyroid nodules from 58 patients who had undergone surgery were
evaluated. Preoperative parameters, demographic data, ultrasound findings, fine-needle
aspiration biopsy results and apparent diffusion coefficient (ADC) values of the nodules at
DW-MRI were compared with the results from postoperative pathology examinations.
Results: The ‘‘benign group’’ included 50 (76.9%) nodules, while 15 (23.1%) nodules constituted
the ‘‘malignancy group’’. Minimum, maximum and mean ADC values of the nodules
were significantly lower in the malignancy group (p < 0.05). The best cutoff value for the
mean ADC value was 1.33 10-3 mm2/s, with a sensitivity of 66.67%, a specifity of 89.13%, a
positive predictive value of 53.63% and a negative predictive value of 89.13%. A mean ADC
value equal to or lower than 1.33 10-3 mm2/s was associated with 9 times higher risk of
malignancy (odds ratio: 9.111, 95% confidence interval: 2.49-33.21).
Conclusions: The ADC value detected by cervical DW-MRI can be considered a predictive
parameter for the detection of thyroid cancer.