The effect of oxytocin and Kisspeptin-10 in ovary and uterus of ischemia-reperfusion injured rats


Aslan M., Senturk G. E. , Akkaya H., Sahin S., Yilmaz B.

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, cilt.56, ss.456-462, 2017 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 56 Konu: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.tjog.2016.12.018
  • Dergi Adı: TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY
  • Sayfa Sayısı: ss.456-462

Özet

Objective: ischemia/reperfusion (I/R) injuries result in damage to endothelial and parenchymal cells. Oxytocin (OXY) stimulates uterine contraction during parturition and myoepithelial cells during suckling. OXY has been used as a protective antioxidant. Kisspeptin plays a key role in the central control of reproductive functions and onset of puberty. Recent studies show that these reproductive hormones have protective potential as antioxidant. The aim of this study is to investigate the potential protective effects of Kisspeptin and OXY as antioxidants on I/R injured ovary and uterus of female rats.