Angiotensin-converting enzyme insertion/deletion polymorphism has no effect on the risk of atherosclerotic stroke or hypertension


Tascilar N., Dursun A., Ankarali H. , Mungan G., Ekem S., Baris S.

JOURNAL OF THE NEUROLOGICAL SCIENCES, cilt.285, ss.137-141, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 285
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.jns.2009.06.016
  • Dergi Adı: JOURNAL OF THE NEUROLOGICAL SCIENCES
  • Sayfa Sayısı: ss.137-141

Özet

Background and purpose: Stroke is a heterogeneous multifactorial disease. Hence, a large number of candidate genes are involved in stroke pathophysiology, such as blood pressure regulation and atherosclerosis. Although angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism is considered to have a role in hypertension, coronary artery disease, and myocardial infarction, its relationship with cerebrovascular disease and hypertension in Stroke in different ethnic populations is still inconsistent.