Angiotensin-converting enzyme insertion/deletion polymorphism has no effect on the risk of atherosclerotic stroke or hypertension


Tascilar N., Dursun A., Ankarali H. , Mungan G., Ekem S., Baris S.

JOURNAL OF THE NEUROLOGICAL SCIENCES, vol.285, pp.137-141, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 285
  • Publication Date: 2009
  • Doi Number: 10.1016/j.jns.2009.06.016
  • Title of Journal : JOURNAL OF THE NEUROLOGICAL SCIENCES
  • Page Numbers: pp.137-141

Abstract

Background and purpose: Stroke is a heterogeneous multifactorial disease. Hence, a large number of candidate genes are involved in stroke pathophysiology, such as blood pressure regulation and atherosclerosis. Although angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism is considered to have a role in hypertension, coronary artery disease, and myocardial infarction, its relationship with cerebrovascular disease and hypertension in Stroke in different ethnic populations is still inconsistent.