Serum heparanase levels are associated with endothelial dysfunction in patients with obstructive sleep apnea


Ozkok A., Ozkok S., Takir M., Yakar H. I. , KANBAY A.

CLINICAL RESPIRATORY JOURNAL, cilt.12, ss.1693-1699, 2018 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 12 Konu: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/crj.12731
  • Dergi Adı: CLINICAL RESPIRATORY JOURNAL
  • Sayfa Sayıları: ss.1693-1699

Özet

Background and aimObstructive sleep apnea syndrome (OSAS) is well-known to be associated with high risk for cardiovascular (CV) diseases. Heparanase has been recently shown to be related to increased inflammation and vulnerability of the atherosclerotic plaques. Herein we aimed to investigate the relationships between OSAS, heparanase and endothelial dysfunction.